All Products/TB-500
TB-500 10 mg — research peptide vial
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Recovery Peptides

TB-500

Research Grade≥99% PurityLyophilized

Synthetic fragment of thymosin beta-4 used in actin-binding and cell migration assays.

Dosage
$45.00
Quantity
1
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Certificate of Analysis

Third Party Tested by Freedom Diagnostics

LATESTSELECTED DOSAGE
99.44%
Purity
Variant10 mg
Lot #VRP-TB510-001
Labeled10 mg
Actual10.09mg
TestedJan 22, 2026
View COA

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Research Summary

TB-500

Published research data and clinical observations

🔬
Preclinical
Research Phase
Extensive animal data
💉
SC / IP / Topical
Administration
Multiple routes studied
🧬
G-Actin Binding
Key Mechanism
Thymosin Beta-4 fragment
📄
50+
Publications
Peer-reviewed papers
🐁
500+
Subjects Studied
Multiple animal models

What Makes TB-500 Different?

The Science, Simplified

The Body's Repair Signal

TB-500 is the active fragment of Thymosin Beta-4 — a protein found in every nucleated cell. It works by reorganizing the cell's internal skeleton (actin), which controls how cells move to injury sites and build new tissue.

Actin
Primary
G-Actin Sequestration
Cell structural protein
Enables cell migration
Promotes cell proliferation
Drives wound closure
NF-κB
Inhibitor
Inflammatory Pathway
Anti-inflammatory action
Reduces swelling
Prevents excess scarring
Organizes connective tissue
VEGF
Inducer
Angiogenesis
New blood vessel growth
Stem cell mobilization
Hair follicle activation
Cardiac tissue repair
WHY SIZE MATTERS

Travels Anywhere in the Body

Most growth factors only work locally at the injection site. TB-500's small molecular weight lets it travel systemically through tissues:

Promotes cell migration to injury sites regardless of injection location 61% faster wound closure at day 7 vs controls.

TB-500Systemic (any injection site)
BPC-157Local + some systemic
PRPInjection site only

What Researchers Observed

61%
Faster re-epithelialization at day 7
Malinda et al. (1999) full-thickness wound model
Dermal wound closure (day 7)61%
Corneal epithelial healing82%
Hair follicle stem cell migration68%
Cardiac repair post-MI64%
Key Milestones Achieved
Re-epithelialization acceleration85%
42% at day 4, 61% at day 7
Collagen deposition increase78%
Histological assessment
Anti-scarring effect72%
Organized connective tissue vs controls
For context:Philp et al. (2004) demonstrated TB4 promotes angiogenesis, wound healing, and hair follicle development simultaneously. Sosne et al. (2007) confirmed corneal healing via anti-inflammatory NF-kB suppression. Kim & Bhatt (2010) showed enhanced connective tissue organization with reduced myofibroblast appearance.
Trial details: Preclinical studies across dermal, cardiac, corneal, and ligament models, n=20-120 per study
Sources: J Invest Dermatol (1999) doi:10.1046/j.1523-1647.1999.00708.x · Mech Ageing Dev (2004) doi:10.1016/j.mad.2003.11.005 · Ann NY Acad Sci (2010) doi:10.1111/j.1749-6632.2010.05483.x

Compound Information

Technical specifications

🧪 Molecular Profile

What Is TB-500?

TypeSynthetic peptide
CAS Number885340-08-9
Molecular Weight846.97 g/mol
Amino Acids7
FormulaC36H66N10O13
❄️ Storage Requirements

Stability Information

Avoid freeze/thaw cyclesProtect from lightKeep refrigerated
Lyophilized (powder)
-20°C · 24+ months
Reconstituted
2-8°C · ~30 days
📋 Development Status

Where It Stands

PreclinicalResearch Use Only
DeveloperRegeneRx Biopharmaceuticals
Trial ProgramMultiple preclinical
Results50+ studies published
This page summarizes published research for informational purposes only. These products are sold exclusively as research chemicals and are not intended for human consumption. Always consult peer-reviewed literature for complete study details.

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